We wanted to know how Alzheimer's works.
Now we want to prevent it.
Yizhou Yu, OneCarbon's founder, begins his investigation into Alzheimer's Disease during his PhD at the University of Cambridge. It is here we discover the novel connection between Alzheimer's and one-carbon metabolism.
Yizhou uses machine learning to discover that a probiotic bacteria can
be used to support one-carbon metabolism and receieves global recognition.
Winner of CSAR's student award, and 2nd out of 100 at global
Falling Walls Lab finale.
We evolve 1C-01 for over a year, resulting in a bacteria with a specific mechanism - releasing one-carbon metabolites. We win the Trinity Bradfield prize and do first-in-human testing. OneCarbon is established to turn this research into an accessible product for neuronal resilience.
We do our first MVP launch with our local pilot group. OneCarbon is selected to join Alzheimer's Society's Innovation Launchpad programme.
We are looking for early adopters to provide feedback on 1C-01 and learn more about their microbiome. At the same time, we are beginning our clinical validation process.
Award-winning neuroscientist and computational biologist, with over 15 well-cited scientific publications. Over 8 years of experience leveraging computational biology, biochemistry, cell biology, and model organisms to investigate neurodegeneration and ageing.
First class Oxford graduate (Human Sciences). Previous experience in biotech start-ups (iPSCs, and medical interventions in beauty & wellness), as well as financial services (Investment Banking). Motivated by family history of Alzheimer's Disease.
Student doctor with multiple years of experience contributing to clinical research. Repeatedly recognised for his ability to communicate complex science to a breadth of internal and external community members.
First class Oxford graduate (PPE). Previously founded a project management company supporting government contract operations. Financial and operational experience from financial sector roles.
Previously the CEO and co-founder of Redgate Software for 20+ years. Chair at RoboK. Founder and Chief Executive of Cade Hill; Board member of numerous companies in the software and biotech sector.
