Daily supplement

1C-01

A daily supplement, built on a live bacterial strain refined at Cambridge to produce one-carbon metabolites from inside your gut.

Non-GMO Food-grade Vegan Gluten free
One box, 36 capsules · one a day · a month's supply, plus a few extra days
£25.50/month
Save 15% · 71p a day
Free UK delivery over £25 · Cancel anytime · 30-day money-back guarantee
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1C-01 packaging styled with yoghurt bowls, berries, and honey
What it is

A live bacterial strain, made to produce one-carbon metabolites

1C-01 is a food-grade supplement built on a live bacterial strain. We isolated a naturally occurring gut strain and refined it in our Cambridge laboratory so that it produces one-carbon metabolites steadily, from within your own gut. One capsule a day, taken with water.

Inside every capsule

What is inside, and what is not

Potency
~90 billion CFU
When to take
1 capsule, morning
Suitable for
Vegans & vegetarians
Storage
Below 25°C

Inside

1C-01 proprietary strain · 90 billion CFU (0.15 g)
Our active, living powerhouse, refined to produce one-carbon metabolites steadily in the gut.
Vitamin D3 (cholecalciferol) · 1000 IU (500% RI)
Chosen to support the function of the live strain. Vitamin D also contributes to the normal function of the immune system.
Capsule shell (plant-derived HPMC)
Suitable for vegetarians and vegans.

Not inside

Zero GMOs or bio-engineered ingredients
1C-01 is refined entirely through natural, directed evolution, not genetic modification.
Zero allergens and gluten
Completely free from wheat, soya, dairy and other common allergens.
Zero synthetic fillers, binders or artificial colours
Just active biology and the clean fibres needed to sustain it.
How to take it

One capsule, once a day

Step 01

Take one each morning

One capsule with a glass of water. Building it into a fixed daily moment makes it easy to keep up.

Step 02

The strain establishes

The capsule reaches your gut, where the strain begins to establish and produce one-carbon metabolites.

Step 03

Keep it consistent

Like any live bacterial strain, 1C-01 works with steady daily use rather than in a single dose.

What to expect

Everyone is different

We describe what members tell us about their experience, not a promised result.

Days 1–7

Settling in

The live strain begins to establish. Some people notice early changes to their routine. Everyone is different.

Weeks 4–8

Finding a rhythm

Many members report this is when the daily routine feels most settled and easiest to sustain.

Weeks 8–12

Regular use

The label notes that full benefits develop over 8 to 12 weeks of consistent daily use, as with any live bacterial strain.

Shipped to you

Free UK delivery on orders over £25, sent Royal Mail Tracked 48.

Secure checkout

Secure checkout via Stripe, we never see your card details.

Money-back guarantee

30-day money-back guarantee, no questions asked.

Real people

Questions answered by the OneCarbon team, not a chatbot. Reach us at team@onecarbon.com.

Questions

Before you start

Is 1C-01 a medicine? +
No. 1C-01 is a food supplement, not a drug. It has not been MHRA-approved to diagnose, treat or prevent any disease.
Does it treat or prevent Alzheimer's disease? +
No. 1C-01 is a food supplement and makes no disease claims. Our team's research explores the underlying biology of one-carbon metabolism and brain ageing, and that work is described on our research page.
Can I take it alongside my medication? +
1C-01 is a food-grade supplement rather than a drug. If you are pregnant, breastfeeding or taking medication, please consult your doctor before starting.
Who should not take 1C-01? +
1C-01 is not suitable for children. If you are pregnant, breastfeeding or on medication, consult your doctor first. Do not exceed the recommended daily dose of one capsule.
When might I notice anything? +
Everyone is different, and as with any live bacterial strain it takes time. The label notes that full benefits develop over 8 to 12 weeks of consistent daily use.
How is it shipped and stored? +
UK orders over £25, including both the £25.50/month subscription and the £30 one-time order, ship free by Royal Mail Tracked 48, which aims to arrive within two to three working days. Order before 7pm and we dispatch the same day, Sunday to Friday. Orders after 7pm on Friday are dispatched Sunday for Monday delivery. Store below 25°C, away from sunlight, and refrigerate after opening.
What if it doesn't work for me? +
We offer a 30-day money-back guarantee. If 1C-01 isn't right for you, email team@onecarbon.com within 30 days of delivery for a full refund — no need to send anything back.

Ready to try 1C-01?

A month of daily support for your one-carbon pathway, plus a few extra days. From £25.50/month, subscribe & save, or £30 one-time — both with free UK delivery over £25 and a 30-day money-back guarantee.

Choose your plan →

1C-01 is a food supplement and should not replace a varied, balanced diet and a healthy lifestyle. It has not been approved to treat, cure or prevent any disease. Not suitable for children. If you are pregnant, breastfeeding or taking medication, consult your doctor before starting.