A supplement built from years of neuroscience research at the University of Cambridge.
1C-01 is a living bacterial strain that supports one-carbon metabolism — the pathway that is important for healthy brain ageing.
2-minute quiz
Is 1C-01 right for you?
Answer 5 quick questions and unlock 10% off your first order.
A Cambridge discovery
Our journey started at Cambridge with a fundamental biological breakthrough. One-carbon metabolism is a critical pathway involved in protecting mitochondrial function and sustaining long-term brain health. This discovery was so central to redefining cognitive care that it became our name: OneCarbon.
To harness this power, we engineered a living biological solution. We isolated a naturally occurring gut strain and refined it in our laboratory to continuously produce these essential one-carbon metabolites from within your own body.
83% boost in neuronal health in pre-clinical cell and animal models
Grounded in 5 peer-reviewed Cambridge studies
Piloted in a small human study (15 participants, ages 50–65) — early-stage evidence, not conclusive
Objectively measure your brain health & wellbeing
Brain health check
Complete a baseline cognitive assessment in the app — reaction time, memory, focus, and more. Takes about 15 minutes.
Take 1C-01 daily
One capsule each morning with a glass of water, consistently. Morning is best — the probiotic is most active in the AM.
Retest and compare
Repeat the assessment after 4–8 weeks. Your score over time chart shows exactly what's changed.
What to expect
1C-01 starts establishing
Some people notice early changes — everyone is different
Many report more noticeable effects
Common areas include cognitive clarity, memory, general wellbeing
Sustained support
Like any live bacterial strain, it takes time
Why a probiotic
How we think about supplements, and why we built a living one rather than a pill.
Diet is the foundation, but it is a blunt way to reach the one-carbon pathway, and folate levels tends to fall with age.
A pill spikes, then clears, and some people convert the synthetic form less efficiently.
1C-01 is a living strain that makes one-carbon metabolites in your gut, steadily, from within.
This is our rationale, not a proven claim. 1C-01 is a food supplement.
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