Science you can take daily
A supplement built from years of neuroscience research at the University of Cambridge.
1C-01 is a living bacterial strain that supports one-carbon metabolism — the pathway that is important for healthy brain ageing.
A supplement built from years of neuroscience research at the University of Cambridge.
1C-01 is a living bacterial strain that supports one-carbon metabolism — the pathway that is important for healthy brain ageing.
A Cambridge discovery
Our journey started at Cambridge with a fundamental biological breakthrough. One-carbon metabolism is a critical pathway involved in protecting mitochondrial function and sustaining long-term brain health. This discovery was so central to redefining cognitive care that it became our name: OneCarbon.
To harness this power, we engineered a living biological solution. We isolated a naturally occurring gut strain and refined it in our laboratory to continuously produce these essential one-carbon metabolites from within your own body.
83% boost in neuronal health in pre-clinical cell and animal models
Grounded in 5 peer-reviewed Cambridge studies
Piloted in a small human study (15 participants, ages 50–65) — early-stage evidence, not conclusive
Objectively measure your brain health & wellbeing
Brain health check
Complete a baseline cognitive assessment in the app — reaction time, memory, focus, and more. Takes about 15 minutes.
Take 1C-01 daily
One capsule each morning with a glass of water, consistently. Morning is best — the live cultures are most active in the AM.
Retest and compare
Repeat the assessment after 4–8 weeks. Your score over time chart shows exactly what's changed.
What to expect
1C-01 starts establishing
Some people notice early changes — everyone is different
Many report more noticeable effects
Common areas include cognitive clarity, memory, general wellbeing
Sustained support
Like any live bacterial strain, it takes time
Why live cultures
How we think about supplements, and why we built a living one rather than a pill.
Diet is the foundation, but it is a blunt way to reach the one-carbon pathway, and folate levels tends to fall with age.
A pill spikes, then clears, and some people convert the synthetic form less efficiently.
1C-01 is a living strain that makes one-carbon metabolites in your gut, steadily, from within.
This is our rationale, not a proven claim. 1C-01 is a food supplement.
Try it with confidence
Baseline your own brain-health check in the app and track it over time. Not satisfied? See our refund terms.
30-day money-back guarantee — no questions asked.
Questions first?
Send us a message and we'll get back to you personally — no bots, no forms to chase.
Contact usJoin our mailing list for research updates and news from OneCarbon.
